Eplerenone in chronic renal disease: the EVALUATE trial
نویسندگان
چکیده
منابع مشابه
Chronic Kidney Disease Requiring Healthcare Services: A New Approach to Evaluate Epidemiology of Renal Disease
BACKGROUND Screening-based CKD estimates may not provide a sufficient insight into the impact of CKD on the use of healthcare resources in clinical practice. The aim of this study was to evaluate the epidemiology of "medicalized" CKD, that is, CKD requiring healthcare services, in an outpatient setting. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS This is a retrospective, longitudinal popu...
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Background: Different types of corticosteroids with different characteristics, such as hydrocortisone and dexamethasone, have been used in treatment of exacerbated chronic obstructive pulmonary disease but drug of choice unclear. The main goal of present study was to compare the efficacy of hydrocortisone and dexamethasone on clinical symptoms, peak expiratory flow, oxidative stress factors and...
متن کاملChronic Renal Disease: Orthomolecular Ramifications
Introduction Increasingly, human kidneys are under assault from environmental toxins as well as an array of diseases that place them at risk of ultimately failing. Eleven percent of American adults now show evidence of chronic kidney disease, with over 400,000 afflicted with end-stage kidney disease. Over a third of those cases are caused by diabetes, and the remainder by high blood pressure an...
متن کاملEplerenone Attenuates Pulse Wave Reflection in Chronic Kidney Disease Stage 3–4 - A Randomized Controlled Study
BACKGROUND Patients with chronic kidney disease (CKD) have high cardiovascular mortality and morbidity associated with increased arterial stiffness. Plasma aldosterone levels are increased in CKD, and aldosterone has been found to increase vascular inflammation and fibrosis. It was hypothesized that aldosterone receptor inhibition with eplerenone could reduce arterial stiffness in CKD stage 3-4...
متن کاملIron absorption in chronic renal disease.
1. Absorption of inorganic iron was studied in thirty-four patients with chronic renal failure by a double isotope technique. 2. Eight patients with normal iron balance had a mean absorption of 3-5%, ten patients with iron overload had a mean absorption of 3.6%, and sixteen patients with iron depletion had a mean absorption of 58%. Thus, alterations in absorption appeared to be related to distu...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2010
ISSN: 0916-9636,1348-4214
DOI: 10.1038/hr.2010.71